Expresión de búsqueda: ANTIBODIES, MONOCLONAL, HUMANIZED 
Descriptores Encontrados: 1
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Descriptor Inglés:   Antibodies, Monoclonal, Humanized 
Descriptor Español:   Anticuerpos Monoclonales Humanizados 
Descriptor Portugués:   Anticorpos Monoclonais Humanizados 
Sinónimos Inglés:   Humanized Antibodies
Antibodies, Humanized  
Categoría:   D12.776.124.486.485.114.224.060
D12.776.124.790.651.114.224.060
D12.776.377.715.548.114.224.200
Definición Inglés:   Antibodies from non-human species whose protein sequences have been modified to make them nearly identical with human antibodies. If the constant region and part of the variable region are replaced, they are called humanized. If only the constant region is modified they are called chimeric. INN names for humanized antibodies end in -zumab. 
Nota Histórica Inglés:   2012 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CH chemistry CL classification
CT contraindications DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número del Registro:   54578 
Identificador Único:   D061067 

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